QUIXIL® Solutions for Sealant

(Human Fibrinogen; Human Thrombin)

QUIXIL® Solutions for Sealant is a fibrin sealant for haemostasis in surgery: it is used as supportive treatment in surgery where standard surgical techniques are insufficient, for improvement of haemostasis. Efficacy has been demonstrated in liver surgery and orthopaedic surgery.

The QUIXIL® Solutions for Sealant Kit consists of:

• a package containing two components in separate vials
  1. Biological Active Component (BAC) – a concentrated solution of Human clottable proteins (mainly fibrinogen and fibronectin) and an antifibrinolytic agent (Tranexamic acid)
  2. Human Thrombin – a high potency solution of purified Human thrombin and calcium chloride for activation of clotting of the final combined product
• a CE marked device package containing the equipment necessary for product application.

Once combined, the BAC and Human Thrombin solutions immediately begin to form fibrin, a natural body protein which is responsible for clotting.

QUIXIL® Solutions for Sealant:

• is 100% free from animal components
• provides immediate fibrin formation
• works independently of the body’s coagulation system
• obtains local haemostasis even in patients receiving pre-op heparin

Contraindications

Products containing Tranexamic acid should not be used in neurosurgery or surgical procedures where contact with cerebro spinal fluid or dura mater can occur (e.g. otologic, rhinologic, ophthalmic and vertebral surgery) due to the risk of cerebral neurological toxicity (such as oedema and seizure).

Please see Summary of Product Characteristics for detailed information.

For more information about QUIXIL® Solutions for Sealant, please view the files below:

• Summary of Product Characteristics
• QUIXIL® Solutions for Sealant Brochure (UK version)