PRINEO Skin Closure System

PRINEO is intended to replace subcuticular/intradermal suturing where there is no tension on the incision/wound or when tension has been relieved by deep dermal or subcutaneous sutures. The system provides a microbial barrier and maintains skin approximation until removed.

• PRINEO reduces subcuticular closure time by 75% as compared to subcuticular suturing (running or interrupted)
• PRINEO enables patients to shower immediately following a procedure
• PRINEO provides a microbial barrier
• PRINEO supports equivalent subcuticular incision/wound closure strength to 3-0 sutures

^{The PRINEO skin closure system consists of two components: 1) a self-adhering mesh packaged within a dispensing applicator and 2) a liquid adhesive (2-octyl cyanoacrylate) packaged within a pen applicator. These two components are supplied together in a sterile, single-use package for use in wound closure procedures.}

For clinical information about PRINEO, view the information below.

 Application

Prior to application of the PRINEO skin closure system, skin tension is relieved through approximation of internal tissue layers as necessary. The mesh is then applied topically to the approximated skin edges using the applicator, where the mesh adheres to the skin using a pressure sensitive adhesive. After the mesh is placed over the wound, the liquid adhesive is applied to the mesh with the pen applicator to complete device application. Once the liquid adhesive has set on the mesh (approximately 30 seconds), the final product is a flexible, mesh-reinforced skin closure device that provides a microbial barrier and maintains skin approximation until removed.

PRINEO Application sheet.pdf